Controlling Blood Clotting
College of Agricultural and Life Sciences
Through the misfortune of a Wisconsin farmer, biochemist Karl Paul Link and his University of Wisconsin associates were handed the keys to discovery of anticlotting factors. Farmer Ed Carlson in February 1933 brought to Link sweet clover hay that he thought might be involved in the death of his cattle from uncontrollable bleeding. Link and students isolated and identified dicumarol as the anticlotting agent in the spoiled hay. Link, and biochemists Mark Stahmann and M. Ikawa, then syndicated comparable compounds including Warfarin, which is widely used to treat thrombosis and other clotting disorders. It also proved to be a highly effective rodenticide.
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Marker is at the intersection of University Avenue and Babcock Drive, on the right when traveling west on University Avenue.
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