Dr. William Monroe Wells was one of the first African American physicians to live in Orlando. Wells moved to Orlando in 1917 and constructed his home in 1921 at 407 West South Street. After obtaining a building permit in 1926, Wells also constructed the South Street Casino and Wells'Built Hotel, which housed many famous African American entertainers during the segregation era in Orlando. The Casino and hotel stood one block from his home until the casino was demolished in 1987. In 2002 the house was moved to 519 West South Street, where the casino had previously stood. The popular foursquare-style home was built by contractor James Murrell, who also constructed the Landmark Maxley-Crooms house. In 2003 the house was registered as an Orlando historic landmark. The Wells'Built Hotel became a museum in 2009.