Despite the growth of other cities in Arizona like Tempe and Phoenix for an example, Guadalupe has remained, quite similar to how it was post world war era.

Guadalupe is a small and inconspicuous town just off interstate 10. However, once you drive down the streets, you might feel like you have left industrialized America and entered a small Mexican town that is full of brightly colored and culturally inspired graffiti art and Spanish-style churches that represent the unique heritage of the community. Yaqui Indians fleeing Sonora in Mexico from persecution of the government settled in the area around 1900 named the town after the Virgin of Guadalupe, the patron saint of Mexico.

These Indians brought with them their own culture as well as the culture of the Franciscans and Spanish missionaries. Today, Native People and people of Spanish ethnicity mostly make up the small community, allowing intermarriages between the two a common practice. It is likely to come across a number of residences that are trilingual, speaking Yaqui, Spanish and English.

Guadalupe has very rich and strong culture, despite the present of the commercialized economies outside their square mile of town. The community expresses their culture during religious ceremonies such as the Easter Parade and final sacraments for the sick and dead that allow the ceremonial last meal held family at midnight.

Community leaders have tried to preserve their history. Inside the Arizona Historical Society-Papago Park, there exists an active small manuscript collection concerned with the preservation of the Yaqui Language and Culture in Guadalupe. This preservation of their unique hybrid of Mexican and Yaqui Native People history is central to the ideals of the community.